Here is the abstract and citation in the journal Obesity. They observed
that in addition to greater weight loss with the LCKD (low carbohydrate,
ketogenic diet), there were also more improvements in negative affect
and reduced hunger in the LCKD. Robert C. Atkins was included as an author.
============================ Abstract ===============
http://www.obesityresearch.org/cgi/c...tract/15/1/182
Obesity 15:182-187 (2007)
© 2007 The North American Association for the Study of Obesity
Original Articles
The Effects of a Low-Carbohydrate Ketogenic Diet and a Low-Fat Diet on
Mood, Hunger, and Other Self-Reported Symptoms
F. Joseph McClernon*, William S. Yancy, Jr.{dagger},{ddagger},
Jacqueline A. Eberstein§, Robert C. Atkins§ and Eric C. Westman{ddagger}
* Departments of Psychiatry and Behavioral Sciences and
{ddagger} Medicine, Duke University Medical Center, Durham, North Carolina;
{dagger} Center for Health Services Research in Primary Care, Department
of Veterans’ Affairs Medical Center, Durham, North Carolina; and
§ Atkins Health & Medical Information Services, New York, New York.
Address correspondence to Eric C. Westman, Duke University Medical
Center, Suite 210-B Wing, 2200 West Main Street, Durham, NC 27705.
E-mail:
Objective: To investigate the effects of weight loss diets on mood, food
cravings, and other self-reported symptoms.
Research Methods and Procedures: Mood and other symptoms were evaluated
by participant self-report using the Atkins Health Indicator Test (AHIT)
in individuals undergoing weight loss following either a
low-carbohydrate, ketogenic diet (LCKD) or a low-fat diet (LFD).
Participants were 119 overweight community volunteers randomized to an
LCKD or an LFD. An additional 51 participants who had completed an
earlier trial contributed data for the psychometric analyses but were
not included in the prospective analyses. Self-reported symptom levels
on seven scales factor-analytically derived from the AHIT (negative
affect, fatigue, somatic symptoms, physical effects of hunger, insomnia,
hunger, and stomach problems) were acquired during 12 visits.
Results: After adjusting for the change in BMI over the course of the
trial, participants experienced significant improvements in most
symptoms regardless of diet. Diet group x visit interactions were
observed for negative affect [F(9,803) = 2.30, p = 0.015] and hunger
[F(9,803) = 3.62, p 0.0002]. Examination of means indicated that the
LCKD group reported less negative affect and hunger, compared with the
LFD group.
Discussion: Regardless of diet, participants experienced significant
improvement in a broad range of symptoms. Symptoms of negative affect
and hunger improved to a greater degree in patients following an LCKD
compared with those following an LFD. Whether these symptom changes
explain the greater short-term weight loss generally experienced by LCKD
followers deserves further research.
Key Words: diet • low-carbohydrate diet • mood • hunger