Excess fat burning leads to insulin resistance

I found this press release describing the results of a study performed
by Dr. Marc Montminy at the Salk Institute. It suggests that:

"Too much fat released from storage into the bloodstream for burning
impedes insulin's ability to promote the uptake of glucose by muscles
and other body organs, resulting in insulin resistance and,
eventually, diabetes. "

http://www.eurekalert.org/pub_releas...-snd111003.php

It's not clear to me why the induced resistance isn't a temporary
effect. Does anyone have any additional information?

Chuck
180/169/155 low carbing but cautious.

Chuck,

Research reported in Lyle MacDonald's book, THE KETOGENIC DIET, showed that
there is a temporary rise in insulin resistance after a period of low
carbing which goes away in a couple days and is attributed to a lack of some
enzymes needed to metabolise the unexpected carb load. This has been
misinterpreted in the way that the article you cited describes.

My own experience after low carbing for 3 years, going off the diet for a
year, and then coming back to it backs up the concept that the increase in
insulin resistance is, indeed, temporary. While I was not low carbing, my
blood sugar response to a known carb load was less than while I was low
carbing, but while low carbing it will be higher.

BUT, while not low carbing, those carbs were very damaging to my health even
though my blood sugar didn't rise as high in response to a given carb dose.
A year of exposure to blood sugars that were in the range the American
Diabetes Association recommends as excellent control caused permanent
deterioration in my fasting blood sugar and blood pressure--which had
remained stable through the 3 years of low carbing.

Bottom line: ignore the claim that low carbing worsens blood sugar and
insulin resistance. It doesn't. In fact, it preserves what is left for those
of us in the early stages of diabetes.

-- Jenny - Low Carbing for 4 years. At goal for weight. Type 2 diabetes,
hba1c 5.2.
Cut the carbs to respond to my email address!

Low carb facts and figures, my weight-loss photos, tips, recipes,
strategies for dealing with diabetes and more at
http://www.geocities.com/jenny_the_bean/

Looking for help controlling your blood sugar?
Visit http://www.alt-support-diabetes.org/...0Diagnosed.htm



"Charles Henkel" wrote in message
...

I found this press release describing the results of a study performed
by Dr. Marc Montminy at the Salk Institute. It suggests that:

"Too much fat released from storage into the bloodstream for burning
impedes insulin's ability to promote the uptake of glucose by muscles
and other body organs, resulting in insulin resistance and,
eventually, diabetes. "

http://www.eurekalert.org/pub_releas...-snd111003.php

It's not clear to me why the induced resistance isn't a temporary
effect. Does anyone have any additional information?

Chuck
180/169/155 low carbing but cautious.